Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 10 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1.3 g
2%*
Polyunsaturated Fat
1 g
†
Monounsaturated Fat
<0.5 g
†
Evening Primrose Oil(Oenothera biennis) (Seed) (Cold-Pressed, Hexane-Free)
1.3 g (1,300 mg)
†
Gamma Linolenic Acid (GLA)
120 mg
†
Top Medical Research Studies
9
We explored how evening primrose oil might affect blood clotting in rabbits fed a high-cholesterol diet. Using a group of 40 rabbits, we supplemented their diet for 6 weeks with evening primrose oil.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
Read More
8
Evening primrose oil reduces clotting risk
We investigated how evening primrose oil (EPO) influences blood clotting when paired with celecoxib, a medication linked to thrombotic events. Using a mouse model, we administered celecoxib alongside EPO or forskolin for four weeks, followed by a prothrombotic challenge.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Read More
8
We examined the effects of evening primrose oil (EPO) on blood platelet aggregation, a key factor in blood clot formation. Over six weeks, 40 male rabbits were divided into groups and fed either a normal diet or an atherogenic diet, with some receiving EPO.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
Read More
Most Useful Reviews
9
Less painful periods
18 people found this helpful
I am 44 and have endometriosis, resulting in heavy, prolonged periods that led to anaemia. After starting evening primrose oil, my menstrual blood loss decreased significantly, and the duration diminished to 3-4 days. I will keep taking it as I noticed a difference in my condition.
Read More
9
Prevented blood clots
5 people found this helpful
Evening primrose oil is excellent for women's hormonal balance, alleviating PMS and menopause symptoms. It helps prevent blood clots, normalises blood pressure, and boosts skin health. It also promotes rapid healing and improves mood, offering numerous health benefits. The product quality is undoubtedly high.
Read More
9
Balanced hormones
5 people found this helpful
Evening primrose oil primarily normalises hormonal balance, reducing PMS and menopause symptoms while aiding in blood pressure regulation and skin health. Its antioxidant effects protect cells, and it helps with mood and sleep. I recommend it for noticeable quality improvements from the start!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
9
We explored how evening primrose oil might affect blood clotting in rabbits fed a high-cholesterol diet. Using a group of 40 rabbits, we supplemented their diet for 6 weeks with evening primrose oil.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
Read More
8
Evening primrose oil reduces clotting risk
We investigated how evening primrose oil (EPO) influences blood clotting when paired with celecoxib, a medication linked to thrombotic events. Using a mouse model, we administered celecoxib alongside EPO or forskolin for four weeks, followed by a prothrombotic challenge.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Read More
8
We investigated how evening primrose oil (EPO) affects blood clotting and blood pressure fluctuations caused by celecoxib in rats. Our study showed that celecoxib raised blood pressure and sped up blood clotting by increasing platelet activity. While EPO helped lower blood pressure and reduced platelet aggregation, omega-3 fatty acids did not have the same effect. This suggests EPO could be a helpful supplement to mitigate cardiovascular risks linked to celecoxib treatment.
Read More
8
We examined the effects of evening primrose oil (EPO) on blood platelet aggregation, a key factor in blood clot formation. Over six weeks, 40 male rabbits were divided into groups and fed either a normal diet or an atherogenic diet, with some receiving EPO.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
Read More
7
Evening primrose oil shows limited effectiveness
We explored the impact of evening primrose oil (EPO) on patients with Raynaud's phenomenon (RP) by conducting a double-blind study. Initially, 21 participants received a two-week placebo course. Following this, 11 patients were given EPO for eight weeks while 10 continued with placebo. Overall, those on EPO reported fewer attacks during colder weather and reported improvements in symptoms.
However, objective measures like hand temperatures and blood flow tests didn't show significant improvement. While there were some observed antiplatelet effects and changes in platelet behavior, the treatment did not lead to marked changes in blood clotting relevant to blood flow improvement.
However, objective measures like hand temperatures and blood flow tests didn't show significant improvement. While there were some observed antiplatelet effects and changes in platelet behavior, the treatment did not lead to marked changes in blood clotting relevant to blood flow improvement.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Less painful periods
18 people found this helpful
I am 44 and have endometriosis, resulting in heavy, prolonged periods that led to anaemia. After starting evening primrose oil, my menstrual blood loss decreased significantly, and the duration diminished to 3-4 days. I will keep taking it as I noticed a difference in my condition.
Read More
9
Prevented blood clots
5 people found this helpful
Evening primrose oil is excellent for women's hormonal balance, alleviating PMS and menopause symptoms. It helps prevent blood clots, normalises blood pressure, and boosts skin health. It also promotes rapid healing and improves mood, offering numerous health benefits. The product quality is undoubtedly high.
Read More
9
Balanced hormones
5 people found this helpful
Evening primrose oil primarily normalises hormonal balance, reducing PMS and menopause symptoms while aiding in blood pressure regulation and skin health. Its antioxidant effects protect cells, and it helps with mood and sleep. I recommend it for noticeable quality improvements from the start!
Read More
9
Improved cycle regularity
4 people found this helpful
After beginning evening primrose oil due to heavy menstrual discharge and clots, I saw positive changes. The colour of my menstrual flow improved, the cycle regularised to 25-28 days, and it appears to be beneficial for menopausal symptoms as well, thanks to its immune-supporting properties.
Read More
9
Life-changer
2 people found this helpful
After only two days of using evening primrose oil, I noticed it helped with irregular periods, heavy bleeding, and PMS symptoms. My mood improved significantly and I'm no longer experiencing severe abdominal cramps or extreme blood loss during my period. I feel it's changing my life for the better.
Read More
Frequently Asked Questions
9
Life-changer
2 people found this helpful
After only two days of using evening primrose oil, I noticed it helped with irregular periods, heavy bleeding, and PMS symptoms. My mood improved significantly and I'm no longer experiencing severe abdominal cramps or extreme blood loss during my period. I feel it's changing my life for the better.
9
Improved cycle regularity
4 people found this helpful
After beginning evening primrose oil due to heavy menstrual discharge and clots, I saw positive changes. The colour of my menstrual flow improved, the cycle regularised to 25-28 days, and it appears to be beneficial for menopausal symptoms as well, thanks to its immune-supporting properties.
7.5
Decreased menstrual pain
15 people found this helpful
After surgery for endometriosis, my doctor recommended evening primrose oil. I noticed no unpleasant aftertaste. Over 7-8 months, I've had less premenstrual and period pain, and the amount of blood and days of menstruation has decreased. I feel more balanced and recommend this product to others.
9
Less painful periods
18 people found this helpful
I am 44 and have endometriosis, resulting in heavy, prolonged periods that led to anaemia. After starting evening primrose oil, my menstrual blood loss decreased significantly, and the duration diminished to 3-4 days. I will keep taking it as I noticed a difference in my condition.
9
Prevented blood clots
5 people found this helpful
Evening primrose oil is excellent for women's hormonal balance, alleviating PMS and menopause symptoms. It helps prevent blood clots, normalises blood pressure, and boosts skin health. It also promotes rapid healing and improves mood, offering numerous health benefits. The product quality is undoubtedly high.
7.5
Reduced blood loss
118 people found this helpful
I bought this primrose on the advice of my gynaecologist for my endometriosis, which caused heavy and painful periods. After taking one capsule with meals, I noticed a significant reduction in blood loss and pain. Additionally, my facial skin has improved. I will continue using it for better health.
7.5
Reduced period pain
I take evening primrose oil a week before and after my period to help with nutrition and recovery after losing blood. Previously, I relied on painkillers on the first day, but now the pain is minimal and manageable, with improved blood flow.
7.5
Normalised cycle
15 people found this helpful
I have no complaints about the quality of this product; the capsules are large but easy to swallow. After three months of taking two capsules a day, my cycle has normalised, and my hair and nails improved. My cholesterol also dropped. I will buy more.
8
Evening primrose oil reduces clotting risk
We investigated how evening primrose oil (EPO) influences blood clotting when paired with celecoxib, a medication linked to thrombotic events. Using a mouse model, we administered celecoxib alongside EPO or forskolin for four weeks, followed by a prothrombotic challenge.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
8
We investigated how evening primrose oil (EPO) affects blood clotting and blood pressure fluctuations caused by celecoxib in rats. Our study showed that celecoxib raised blood pressure and sped up blood clotting by increasing platelet activity. While EPO helped lower blood pressure and reduced platelet aggregation, omega-3 fatty acids did not have the same effect. This suggests EPO could be a helpful supplement to mitigate cardiovascular risks linked to celecoxib treatment.
9
We explored how evening primrose oil might affect blood clotting in rabbits fed a high-cholesterol diet. Using a group of 40 rabbits, we supplemented their diet for 6 weeks with evening primrose oil.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
8
We examined the effects of evening primrose oil (EPO) on blood platelet aggregation, a key factor in blood clot formation. Over six weeks, 40 male rabbits were divided into groups and fed either a normal diet or an atherogenic diet, with some receiving EPO.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
References
- Mosaad SM, Zaitone SA, Ahmed AA, Abo-Elmatty DM, El-Baz AA, et al. Evening primrose oil or forskolin ameliorates celecoxib-enhanced upregulation of tissue factor expression in mice subjected to lipopolysaccharide-induced endotoxemia. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:483. doi:10.1007/s00210-017-1342-y
- Zaitone SA, Moustafa YM, Mosaad SM, El-Orabi NF. Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. J Cardiovasc Pharmacol. 2011;58:72. doi:10.1097/FJC.0b013e31821c8353
- Villalobos MA, De La Cruz JP, Martín-Romero M, Carmona JA, Smith-Agreda JM, et al. Effect of dietary supplementation with evening primrose oil on vascular thrombogenesis in hyperlipemic rabbits. Thromb Haemost. 1998;80:696.
- De La Cruz JP, Martín-Romero M, Carmona JA, Villalobos MA, Sánchez de la Cuesta F. Effect of evening primrose oil on platelet aggregation in rabbits fed an atherogenic diet. Thromb Res. 1997;87:141.
- Belch JJ, Shaw B, O'Dowd A, Saniabadi A, Leiberman P, et al. Evening primrose oil (Efamol) in the treatment of Raynaud's phenomenon: a double blind study. Thromb Haemost. 1985;54:490.
